NM23-H1 Antibody (084)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89930

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 084

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NM23-H1 Antibodies »

Product Summary for NM23-H1 Antibody (084)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human NM23-H1 (Accession#: NP_000260.1; Ala2-Glu152).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for NM23-H1 Antibody (084)

Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930]

Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930]

Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930] - Staining of human NME1 in human hepatoma with rabbit monoclonal antibody (1:200).
Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930]

Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930]

Immunohistochemistry-Paraffin: NM23-H1 Antibody (084) [NBP2-89930] - Staining of human NME1 in human lung cancer with rabbit monoclonal antibody (1:200).

Applications for NM23-H1 Antibody (084)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NM23-H1

The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and -H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nucleasehypersensitive elements at positions 142 to 115 of the human c-Myc promotor.

Long Name

Non-metastatic Protein 23 Homolog 1

Alternate Names

GAAD, NDKA, NDPKA, NM23A, NM23H1, NME1

Gene Symbol

NME1

Additional NM23-H1 Products

Product Documents for NM23-H1 Antibody (084)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NM23-H1 Antibody (084)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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