Noggin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34141

Novus Biologicals, part of Bio-Techne
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NBP2-34141
NBP2-34141-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Noggin Antibodies »

Product Summary for Noggin Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: GQHYLHIRPAPSDNLPLVDLIEHPDPIFDPKEKDLNETLLRSLLGGHYDPGFMATS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Noggin Antibody

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human prostate shows no positivity in glandular cells as expected.
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human cerebellum shows no positivity in Purkinje cells as expected.
Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141]

Immunohistochemistry-Paraffin: Noggin Antibody [NBP2-34141] - Staining of human cerebral cortex shows weak cytoplasmic positivity in neurons.
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Applications for Noggin Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Noggin

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Alternate Names

NOG, SYM1, SYNS1, SYNS1A

Gene Symbol

NOG

UniProt

Q13253

Additional Noggin Products

Product Documents for Noggin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Noggin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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