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NRAMP1/SLC11A1 Antibody (2G2)

Novus Biologicals, part of Bio-Techne | Catalog # H00006556-M01

Novus Biologicals, part of Bio-Techne
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H00006556-M01

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Bovine

Cited:

Mouse

Applications

Validated:

ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 2G2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

SLC11A1 (NP_000569.2, 308 a.a. ~ 350 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. QAFYQKTNQAAFNICANSSLHDYAKIFPMNNATVAVDIYQGGV

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 23191958).

Localization

Membrane; Multi pass membrane protein.

Specificity

SLC11A1 - solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for NRAMP1/SLC11A1 Antibody (2G2)

Western Blot: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01]

Western Blot: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01]

Western Blot: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01] - SLC11A1 monoclonal antibody (M01), clone 2G2. Analysis of SLC11A1 expression in human liver.
ELISA: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01]

ELISA: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01]

ELISA: NRAMP1/SLC11A1 Antibody (2G2) [H00006556-M01] - Detection limit for recombinant GST tagged SLC11A1 is approximately 0.03ng/ml as a capture antibody.

Applications for NRAMP1/SLC11A1 Antibody (2G2)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: NRAMP1/SLC11A1

This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.

Long Name

Natural Resistance-associated Macrophage Protein 1

Alternate Names

LSH, SLC11A1

Entrez Gene IDs

6556 (Human)

Gene Symbol

SLC11A1

OMIM

600266 (Human)

UniProt

Additional NRAMP1/SLC11A1 Products

Product Documents for NRAMP1/SLC11A1 Antibody (2G2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for NRAMP1/SLC11A1 Antibody (2G2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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