NRIF3 Antibody - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-03238

Novus Biologicals, part of Bio-Techne
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NBP3-03238-100ul
NBP3-03238-20ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

Azide and BSA Free

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NRIF3 Antibodies »

Product Summary for NRIF3 Antibody - Azide and BSA Free

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-111 of human NRIF3 (NP_055103.3). MPVKRSLKLDGLLEENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for NRIF3 Antibody - Azide and BSA Free

Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody [NBP3-03238] - Paraffin-embedded human gastric cancer using NRIF3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody [NBP3-03238] - Paraffin-embedded human liver using NRIF3 antibody at dilution of 1:100 (40x lens).
Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody - Azide and BSA Free [NBP3-03238]

Immunohistochemistry-Paraffin: NRIF3 Antibody [NBP3-03238] - Paraffin-embedded human appendix using NRIF3 antibody at dilution of 1:100 (40x lens).
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Applications for NRIF3 Antibody - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS with 50% glycerol, pH7.3.

Format

Azide and BSA Free

Preservative

0.01% Thimerosal

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: NRIF3

Transcription coregulator that can have both coactivator and corepressor functions. Isoform 1, but not other isoforms, is involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand-dependent fashion. In contrast, it does not coactivate nuclear receptors for retinoic acid, vitamin D, progesterone receptor, nor glucocorticoid. Acts as a coactivator for estrogen receptor alpha. Acts as a transcriptional corepressor via its interaction with the NFKB1 NF-kappa-B subunit, possibly by interfering with the transactivation domain of NFKB1. Induces apoptosis in breast cancer cells, but not in other cancer cells, via a caspase-2 mediated pathway that involves mitochondrial membrane permeabilization but does not require other caspases. May also act as an inhibitor of cyclin A-associated kinase. Also acts a component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex

Alternate Names

beta-3-endonexin, CENP-R, centromere protein R, HSU37139, integrin beta 3 binding protein (beta3-endonexin), Integrin beta-3-binding protein, NRIF3CENPRbeta 3 endonexin, Nuclear receptor-interacting factor 3, TAP20

Gene Symbol

ITGB3BP

Additional NRIF3 Products

Product Documents for NRIF3 Antibody - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for NRIF3 Antibody - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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