NTH1 Antibody (S08-8E9)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19722

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19722-100ul
NBP3-19722-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S08-8E9

Concentration

0.3 mg/ml

View all NTH1 Antibodies »

Product Summary for NTH1 Antibody (S08-8E9)

Immunogen

Recombinant protein of human NTH1 (Uniprot # P78549)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

34 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for NTH1 Antibody (S08-8E9)

Western Blot: NTH1 Antibody (S08-8E9) [NBP3-19722]

Western Blot: NTH1 Antibody (S08-8E9) [NBP3-19722]

Western Blot: NTH1 Antibody (S08-8E9) [NBP3-19722] - Western blot detection of NTH1 in K562, Hela cell lysates using NBP3-19722 (1:1000 diluted). Predicted band size: 34kDa. Observed band size: 34kDa.

Applications for NTH1 Antibody (S08-8E9)

Application
Recommended Usage

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: NTH1

Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites. A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.

Long Name

Nth Endonuclease III-like 1

Alternate Names

NTHL1, OCTS3

Gene Symbol

NTHL1

Additional NTH1 Products

Product Documents for NTH1 Antibody (S08-8E9)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for NTH1 Antibody (S08-8E9)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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