NTH1 Antibody [FITC]

Novus Biologicals, part of Bio-Techne | Catalog # NB100-108F

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB100-108AF350

Alexa Fluor 405

NB100-108AF405

Alexa Fluor 488

NB100-108AF488

Alexa Fluor 532

NB100-108AF532

Alexa Fluor 594

NB100-108AF594

Alexa Fluor 647

NB100-108AF647

Alexa Fluor 700

NB100-108AF700

Alexa Fluor 750

NB100-108AF750

Allophycocyanin

NB100-108APC

Biotin

NB100-108B

DyLight 350

NB100-108UV

DyLight 405

NB100-108V

DyLight 488

NB100-108G

DyLight 550

NB100-108R

DyLight 594

NB100-108DL594

DyLight 650

NB100-108C

DyLight 680

NB100-108FR

DyLight 755

NB100-108IR

HRP

NB100-108H

Janelia Fluor 525

NB100-108JF525

Janelia Fluor 549

NB100-108JF549

Janelia Fluor 585

NB100-108JF585

Janelia Fluor 635

NB100-108JF635

Janelia Fluor 646

NB100-108JF646

Janelia Fluor 669

NB100-108JF669

PE

NB100-108PE

PerCP

NB100-108PCP

Forumulation

Catalog #

BSA Free

NB100-108

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (93%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

FITC (Excitation = 495 nm, Emission = 519 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all NTH1 Antibodies »

Product Summary for NTH1 Antibody [FITC]

Immunogen

A peptide derived from human NTH1, conjugated to KLH. [UniProt# P78549]

Reactivity Notes

Immunogen sequence has 93% identity with bovine proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for NTH1 Antibody [FITC]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: NTH1

NTH1 (endonuclease III-like protein 1 or NTHL1) has both apurinic/apyrimidinic endonuclease activity and a DNA N-glycosylase activity. The C-O-P bond 3' to apurinic or apyrimidinic site in DNA is broken by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. NTH1 associates with 1 4Fe-4S cluster and this cluster has been proposed to involve in proper positioning of enzyme along the DNA strand. With potential for incising damaged DNA at cytosines, thymines and guanines, NTH1 acts on a damaged strand 5' from the damaged site, for playing essential role in repair of both oxidative DNA damage and spontaneous mutagenic lesions. Localized in the nucleus, NTH1 is widely expressed with highest levels in heart and its expression levels are regulated during the cell cycle with increased levels during early and mid S-phase.

Long Name

Nth Endonuclease III-like 1

Alternate Names

NTHL1, OCTS3

Gene Symbol

NTHL1

Additional NTH1 Products

Product Documents for NTH1 Antibody [FITC]

Product Datasheets

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COA

SDS

Product Specific Notices for NTH1 Antibody [FITC]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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