Numb Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30928

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Numb Antibodies »

Product Specifications

Immunogen

Synthetic peptide derived from human Numb protein

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for Numb Antibody

Numb Antibody

Western Blot: Numb Antibody [NBP3-30928] -

Western Blot: Numb Antibody [NBP3-30928] - Western blot using anti-Numb (Cat. No. NBP3-30928) on human brain lysate. Lysate used at 14 ug/lane. Antibody used at 10ug/ml. Secondary antibody, mouse anti-rabbit HRP , used at 1:50k dilution.

Applications for Numb Antibody

Application
Recommended Usage

Western Blot

: 1-5 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Numb

Numb is a transmembrane signaling receptor that is activated by the DSL family of ligands. Studies suggestthat mammalian Numb plays a role in progenitor cell fate in neurogenesis. Numb exerts its role on cell fate by antagonizing Notch signaling. The mammalian Numb gene undergoes alternative splicing to produce at least four functionally different Numb isoforms which regulate different processes. A loss of Numb expression has been demonstrated in breast cancer, non-small cell lung cancer and chronic myelogenous leukemia.

Alternate Names

m-numb, mnb, S171

Gene Symbol

NUMB

Additional Numb Products

Product Documents for Numb Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Numb Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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