Numb Products
Numb is a 75 kDa member of a family of cytoplasmic adaptor proteins termed CLASPS (clathrin-associated sorting proteins). CLASPS link transmembrane cargo proteins to the endocytic machinery. Numb is normally associated with the basolateral surface of polarized cells and has been shown to regulate cell fate by modulating activity of the Notch pathway. Human Numb is 651 amino acids (aa) in length. It contains one phosphotyrosine-binding domain (PTB; aa 24 - 172) and one proline-rich region (PRR; aa 366 - 413). There is a potential for multiple alternate splice forms that involve all regions of the molecule. Over aa 356 - 592, human Numb shares 88% and 90% aa identity with mouse and canine Numb, respectively.
139 results for "Numb" in Products
139 results for "Numb" in Products
Numb Products
Numb is a 75 kDa member of a family of cytoplasmic adaptor proteins termed CLASPS (clathrin-associated sorting proteins). CLASPS link transmembrane cargo proteins to the endocytic machinery. Numb is normally associated with the basolateral surface of polarized cells and has been shown to regulate cell fate by modulating activity of the Notch pathway. Human Numb is 651 amino acids (aa) in length. It contains one phosphotyrosine-binding domain (PTB; aa 24 - 172) and one proline-rich region (PRR; aa 366 - 413). There is a potential for multiple alternate splice forms that involve all regions of the molecule. Over aa 356 - 592, human Numb shares 88% and 90% aa identity with mouse and canine Numb, respectively.
| Reactivity: | Human, Mouse, Chicken |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, Simple Western |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #447716 |
| Applications: | WB, ICC |
| Reactivity: | Human, Mouse, Rat, Bovine, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Numb Antibody [NBP2-27181]](https://resources.bio-techne.com/images/products/NUMB-Antibody-Western-Blot-NBP2-27181-img0004.jpg "Western Blot: Numb Antibody [NBP2-27181]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4F3 |
| Applications: | IHC, WB |
![Western Blot: Numb Antibody (OTI4F3) [NBP2-45877]](https://resources.bio-techne.com/images/products/Numb-Antibody-4F3-Western-Blot-NBP2-45877-img0017.jpg "Western Blot: Numb Antibody (OTI4F3) [NBP2-45877]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI1B5 |
| Applications: | IHC, WB |
![Western Blot: Numb Antibody (OTI1B5) [NBP2-46284]](https://resources.bio-techne.com/images/products/Numb-Antibody-1B5-Western-Blot-NBP2-46284-img0008.jpg "Western Blot: Numb Antibody (OTI1B5) [NBP2-46284]")
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC |
| Reactivity: | Human |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC |
| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human Numb GST (N-Term) Protein [H00008650-P01]](https://resources.bio-techne.com/images/products/qc_test-H00008650-P01-1.jpg "SDS-PAGE: Recombinant Human Numb GST (N-Term) Protein [H00008650-P01]")
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: Numb Antibody [NBP2-98717]](https://resources.bio-techne.com/images/products/Numb-Antibody-Western-Blot-NBP2-98717-img0002.jpg "Western Blot: Numb Antibody [NBP2-98717]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #9X1Y0 |
| Applications: | WB, IP |
![Western Blot: Numb Antibody (9X1Y0) [NBP3-16738]](https://resources.bio-techne.com/images/products/Numb-Antibody-9X1Y0-Western-Blot-NBP3-16738-img0001.jpg "Western Blot: Numb Antibody (9X1Y0) [NBP3-16738]")
| Reactivity: | Human |
| Details: | Rabbit Polyclonal |
| Applications: | WB |
| Applications: | WB |
![Western Blot: Numb Overexpression Lysate [NBP2-08848]](https://resources.bio-techne.com/images/products/NUMB-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-08848-img0001.jpg "Western Blot: Numb Overexpression Lysate [NBP2-08848]")
| Applications: | WB |
![Western Blot: Numb Overexpression Lysate [NBL1-13870]](https://resources.bio-techne.com/images/products/NUMB-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-13870-img0002.jpg "Western Blot: Numb Overexpression Lysate [NBL1-13870]")
| Applications: | WB |
![Western Blot: Numb Overexpression Lysate [NBP2-08847]](https://resources.bio-techne.com/images/products/NUMB-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-08847-img0001.jpg "Western Blot: Numb Overexpression Lysate [NBP2-08847]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4F3 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4F3 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI1B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4F3 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI1B5 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI1B5 |
| Applications: | IHC, WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI4F3 |
| Applications: | IHC, WB |