Olig2 is a transcription factor which is required for oligodendrocyte and motor neuron specification in the spinal cord, as well as for the development of somatic motor neurons in the hindbrain. OIlig2 is expressed in the ventral spinal cord as early as 9.5 dpc and is scattered in the mantle zone, likely corresponding to oligodendrocyte progenitors migrating out from their site of origin. (Arnett et al., 2004) From 10.5 through 14.5 dpc, Olig2 is expressed in numerous cells in the ventricular and subventricular zones of the lateral and medial ganglionic eminences, suggesting that expression might not be limited to the oligodendrocytic lineage. Olig2 has further been shown to be critical in the proliferation of malignant glioma in brain tumors (Ligon et al., 2007).

Long Name

Oligodendrocyte Lineage Transcription Factor 2

Alternate Names

BHLHB1, PRKCBP2, RACK17

Gene Symbol

OLIG2

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Product Documents for Olig2 Antibody (OLIG2/7366R) [DyLight 488]

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Product Specific Notices for Olig2 Antibody (OLIG2/7366R) [DyLight 488]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Olig2 Antibody (OLIG2/7366R) [DyLight 488]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20891G

Key Product Details

Species Reactivity

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Product Specifications

Immunogen

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Applications for Olig2 Antibody (OLIG2/7366R) [DyLight 488]

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

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Stability & Storage

Background: Olig2