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ORF73/HHV8 Antibody (LN53) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-22767

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Virus

Applications

Immunoassay, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2C Clone # LN53

Format

BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Recombinant protein corresponding to the latent nuclear antigen-1 molecule of HHV8.

Localization

Nuclear

Specificity

This antibody reacts with ORF-73 of human Herpes virus 8 (HHV8). HHV8 is the likely etiological agent of Kaposi's sarcoma (KS). HHV8 encodes a latent nuclear antigen (LNA) which is the product of the viral gene orf 73. LNA is capable of forming a complex with retinoblastoma susceptibility gene product which may be related to its oncogenic activity.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2C

Scientific Data Images for ORF73/HHV8 Antibody (LN53) - BSA Free

Immunohistochemistry-Paraffin: ORF73/HHV8 Antibody (LN53) - BSA Free [NBP1-22767]

Immunohistochemistry-Paraffin: ORF73/HHV8 Antibody (LN53) - BSA Free [NBP1-22767]

Immunohistochemistry-Paraffin: ORF73/HHV8 Antibody (LN53) [NBP1-22767] - Cultured cells infected with HHV8 stained with HHV8 antibody

Applications for ORF73/HHV8 Antibody (LN53) - BSA Free

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: ORF73 HHV8

HHV8 has been found to be associated with three different diseases observed in AIDS patients; kaposi's sarcoma, primary effusion lymphoma (which is a rare type of non-Hodgkin lymphoma affecting the body cavities) and multicentric Castleman's disease. To date there is much evidence to support a direct role for HHV8 in kaposi's sarcoma.

Long Name

ORF73 of Human Herpesvirus 8

Alternate Names

HHV8GK18_gp81, LANA1

Gene Symbol

HHV8gp78

Additional ORF73 HHV8 Products

Product Documents for ORF73/HHV8 Antibody (LN53) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for ORF73/HHV8 Antibody (LN53) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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