Ornithine Carbamoyltransferase Antibody (CL4046)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-59039

Novus Biologicals, part of Bio-Techne
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NBP2-59039
NBP2-59039-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL4046

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Ornithine Carbamoyltransferase/OTC Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence:ILADYLTLQEHYSSLKGLTLSWIGDGNNILHSIMMSAAKFGMHLQAATPKGYEPDASVTKLAEQYAKENGTKLLLTNDPLEAAHGGNVLITDTWISMGQEEEKKKRLQAFQGYQVTMKTAKVAASDWT

Epitope

GYEPDASVTKLAEQY

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Ornithine Carbamoyltransferase Antibody (CL4046)

Western Blot: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Western Blot: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Western Blot: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039] - Analysis in human liver tissue.
Immunocytochemistry/ Immunofluorescence: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Immunocytochemistry/ Immunofluorescence: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Immunocytochemistry/Immunofluorescence: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039] - Staining of RH-30 cells using the Anti-OTC monoclonal antibody, showing specific staining in mitochondria in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039]

Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody (CL4046) [NBP2-59039] - Staining of human endometrium shows no positivity as expected (negative control).
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Applications for Ornithine Carbamoyltransferase Antibody (CL4046)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

2-10 ug/ml

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. For ICC/IF, PFA/Triton X-100 is recommended for fixation/permeabilization.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Ornithine Carbamoyltransferase/OTC

This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also. (provided by RefSeq)

Alternate Names

OCTD, Ornithine Transcarbamylase, OTC, OTCase

Gene Symbol

OTC

Additional Ornithine Carbamoyltransferase/OTC Products

Product Documents for Ornithine Carbamoyltransferase Antibody (CL4046)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Ornithine Carbamoyltransferase Antibody (CL4046)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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