Ornithine Carbamoyltransferase Antibody
Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31582
Key Product Details
Species Reactivity
Validated:
Human, Mouse
Cited:
Human, Mouse, Primate
Predicted:
Bovine (94%), Porcine (94%), Rat (93%). Backed by our 100% Guarantee.
Applications
Validated:
Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
Recombinant protein encompassing a sequence within the center region of human Ornithine Carbamoyltransferase. The exact sequence is proprietary.
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: Chicken (80%).
Localization
Mitochondrion matrix
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Scientific Data Images for Ornithine Carbamoyltransferase Antibody
Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-31582]
Immunohistochemistry-Paraffin: Ornithine Carbamoyltransferase Antibody [NBP1-31582] - Paraffin-embedded Colon ca, using antibody at 1:250 dilution.Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-31582]
Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-31582] - Hepatic metabolic response during infection. Mice (n=4/group) matched for intake +/- infection with PR8 influenza were euthanized at Day 5 and livers were harvested. Immunoblot of CPS1 and OTC (Ornithine Carbamoyltransferase) protein. Image collected and cropped by CiteAb from the following publication (https://dmm.biologists.org/cgi/doi/10.1242/dmm.013003) licensed under a CC-BY license.Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-31582] -
Western Blot: Ornithine Carbamoyltransferase Antibody [NBP1-31582] - OTC enzyme & biochemical parameters in spf-J males.Spf-J & WT were maintained on a regular chow diet (22% protein) & euthanized at 8 weeks. Blood was collected by retro-orbital bleeding with plasma separated & stored at −80°C until use. Tissues were snap frozen & stored at −80°C until use. A) mRNA level in spf-J (N = 4) & WT (N = 4) livers. B) Immunoblot of OTC protein. C) OTC enzyme activity in liver homogenates from spf-j (N = 6) & WT (N = 4). D) Plasma ammonia in spf-j (N = 7) & WT (N = 6). E) Plasma orotate in spf-j (N = 5) & WT (N = 6). Hatched bar indicates P < 0.05. WT – wild-type. Image collected & cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0116594), licensed under a CC0-1.0 license. Not internally tested by Novus Biologicals.Applications for Ornithine Carbamoyltransferase Antibody
Application
Recommended Usage
Immunohistochemistry
1:100-1:1000
Immunohistochemistry-Frozen
Assay dependent
Immunohistochemistry-Paraffin
1:100-1:1000
Western Blot
1:500-1:30000
Formulation, Preparation, and Storage
Purification
Antigen Affinity-purified
Formulation
PBS, 20% Glycerol
Preservative
0.025% Proclin 300
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Background: Ornithine Carbamoyltransferase/OTC
Alternate Names
OCTD, Ornithine Transcarbamylase, OTC, OTCase
Entrez Gene IDs
5009 (Human)
Gene Symbol
OTC
UniProt
Additional Ornithine Carbamoyltransferase/OTC Products
Product Documents for Ornithine Carbamoyltransferase Antibody
Product Specific Notices for Ornithine Carbamoyltransferase Antibody
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information go to www.P65Warnings.ca.gov.