ORP150/HSP12A Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-99781

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all ORP150/HSP12A Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Human ORP150/HSP12A (Accession#: NP_001124463.1; Met 695-Leu 994)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for ORP150/HSP12A Antibody

Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781]

Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781]

Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781] - Immunochemical staining of human ORP150/HSP12A in human liver with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).
Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781]

Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781]

Immunohistochemistry-Paraffin: ORP150/HSP12A Antibody [NBP2-99781] - Immunochemical staining of human ORP150/HSP12A in human breast carcinoma with rabbit polyclonal antibody (1:5000, formalin-fixed paraffin embedded sections).

Applications for ORP150/HSP12A Antibody

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry-Paraffin

1:2500-1:10000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: ORP150/HSP12A

HYOU1 is encoded by this gene belongs to the heat shock protein 70 family. This gene uses alternative transcription start sites. A cis-acting segment is found at the 5' end of the first exon, and is involved in stress-dependent induction. A transcript that is produced from a downstream start site is preferentially induced by hypoxia, resulting in the accumulation of this protein in the endoplasmic reticulum (ER). The protein encoded by this gene is thought to play an important role in protein folding and secretion in the ER. Since suppression of the protein is associated with accelerated apoptosis, it is also suggested to have an important cytoprotective role in hypoxia-induced cellular perturbation. This protein has been shown to be up-regulated in tumors, especially in breast tumors, and thus it is associated with tumor invasiveness. This gene also has an alternative translation initiation site, resulting in a protein that lacks the signal peptide. This signal peptide-lacking protein, which is only 3 amino acids shorter than the mature protein in the ER, is thought to have a housekeeping function in the cytosol.

Long Name

Oxygen Regulated Protein, 150 kDa

Alternate Names

HSP12A, HYOU1

Gene Symbol

HYOU1

Additional ORP150/HSP12A Products

Product Documents for ORP150/HSP12A Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for ORP150/HSP12A Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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