OXPAT Antibody [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NB110-60509V

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NB110-60509AF350

Alexa Fluor 405

NB110-60509AF405

Alexa Fluor 488

NB110-60509AF488

Alexa Fluor 532

NB110-60509AF532

Alexa Fluor 594

NB110-60509AF594

Alexa Fluor 647

NB110-60509AF647

Alexa Fluor 700

NB110-60509AF700

Alexa Fluor 750

NB110-60509AF750

Allophycocyanin

NB110-60509APC

Biotin

NB110-60509B

CoraFluor 1

NB110-60509CL1

DyLight 350

NB110-60509UV

DyLight 488

NB110-60509G

DyLight 550

NB110-60509R

DyLight 594

NB110-60509DL594

DyLight 650

NB110-60509C

DyLight 680

NB110-60509FR

DyLight 755

NB110-60509IR

FITC

NB110-60509F

HRP

NB110-60509H

Janelia Fluor 525

NB110-60509JF525

Janelia Fluor 549

NB110-60509JF549

Janelia Fluor 585

NB110-60509JF585

Janelia Fluor 635

NB110-60509JF635

Janelia Fluor 646

NB110-60509JF646

Janelia Fluor 669

NB110-60509JF669

mFluor Violet 450 SE

NB110-60509MFV450

mFluor Violet 500 SE

NB110-60509MFV500

mFluor Violet 610 SE

NB110-60509MFV610

PE

NB110-60509PE

PerCP

NB110-60509PCP

Forumulation

Catalog #

BSA Free

NB110-60509

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Porcine, Bovine

Predicted:

Sheep (94%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Simple Western, Western Blot

Label

DyLight 405 (Excitation = 400 nm, Emission = 420 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all OXPAT Antibodies »

Product Summary for OXPAT Antibody [DyLight 405]

Immunogen

A synthetic peptide made to a region of the human OXPAT protein, within residues 300-400. [UniProt# Q00G26]

Reactivity Notes

Porcine reactivity reported in scientific literature (PMID: 29094660). Immunogen displays the following percentage of sequence identity for non-tested species: sheep (94%), rat (84%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for OXPAT Antibody [DyLight 405]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Simple Western

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: OXPAT

OXPAT (PLIN5/Perilipin 5) is a novel PAT-1 (Perilipin, ADRP and TIP47) that binds to lipid droplets (LDs) and protects them from lipolytic degradation. The tissue distribution of PAT-1 proteins differs considerably, however, all of them are involved in accumulation and metabolism of lipids in LDs. OXPAT covers LDs in the cytosol and its expression is highest in tissues with a high fat-oxidative capacity, such as heart, oxidative (type I) skeletal muscles and brown adipose tissue wherein the OXPAT contents parallel the LD content. OXPAT overexpression in OP-9 and COS-7 cells increased cellular triglyceride storage in parallel with increases in fatty acid oxidation and induction of gene expression of mitochondrial enzymes involved in oxidative metabolism. OXPAT has the potential of modulating the interaction of the major triacylglycerol lipase ATGL with LD as well as with its co-factor CGI-58 in a well control manner to regulate LD lipolysis. OXPAT expression is up-regulated by PPARalpha, and this regulation appears to be part of an expression program that shifts the metabolism of cells from fatty acid storage to oxidation.

Alternate Names

lipid storage droplet protein 5, LSDA5, LSDP5, MLDP, OXPAT, perilipin 5, perilipin-5

Gene Symbol

PLIN5

Additional OXPAT Products

Product Documents for OXPAT Antibody [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for OXPAT Antibody [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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