p38 beta/MAPK11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-56446

Novus Biologicals, part of Bio-Techne
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NB100-56446
NB100-56446SS
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Applications

Validated:

Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all p38 beta/MAPK11 Antibodies »

Product Specifications

Immunogen

A synthetic peptide corresponding to a portion amino acids 1-100 was used as immunogen,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p38 beta/MAPK11 Antibody

Western Blot: p38 beta/MAPK11 Antibody [NB100-56446]

Western Blot: p38 beta/MAPK11 Antibody [NB100-56446]

Western Blot: p38 beta/MAPK11 Antibody [NB100-56446] - Analysis of p38 beta/MAPK11 in 15 ug of A) human brain and B) mouse brain cell lysate using this antibody.

Applications for p38 beta/MAPK11 Antibody

Application
Recommended Usage

Western Blot

1-3 ug/ml
Application Notes
In human or mouse brain, a 38 kDa band is observed.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS containing 0.2% gelatin

Preservative

0.05% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p38 beta/MAPK11

One of the major signaling pathways used by eukaryotic cells to translate extracellular signals into cellular responses is the MAP (mitogen-activated protein) kinase cascade. So far, four MAPK subgroups (ERK, ERK5, JNK and p38) have been identified in humans. p38 beta is closely related to p38. They differ, however, in that p38 is equally well activated by MKK (MAP kinase kinase) 3, MKK4, and MKK6, while p38 beta is preferentially activated by MKK6. p38 beta also shows a strong substrate preference to ATF2 (activating transcription factor 2). This antibody recognizes MAP11/p38beta; human MAPK11 is a 364 amino acid protein.

Long Name

Mitogen-Activated Protein Kinase 11

Alternate Names

MAPK11, MPK11, p38b, p38beta, PRKM11, SAPK2B

Entrez Gene IDs

5600 (Human); 19094 (Mouse); 689314 (Rat)

Gene Symbol

MAPK11

UniProt

NP_002742

Additional p38 beta/MAPK11 Products

Product Documents for p38 beta/MAPK11 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for p38 beta/MAPK11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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