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p38 beta/MAPK11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98810

Novus Biologicals, part of Bio-Techne
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NBP2-98810-100ul
NBP2-98810-50ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the N-terminus of the Human p38 beta/MAPK11.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for p38 beta/MAPK11 Antibody

Western Blot: p38 beta/MAPK11 Antibody [NBP2-98810]

Western Blot: p38 beta/MAPK11 Antibody [NBP2-98810]

Western Blot: p38 beta/MAPK11 Antibody [NBP2-98810] - Lane A: K562 Whole Cell LysateLysates/proteins at 30 ug per lane.SecondaryGoat Anti- Rabbit IgG H&L (Dylight 800) at 1/10000 dilution.Developed using the Odyssey technique.Performed under reducing conditions.Predicted band size:41 kDaObserved band size:36 kDa
Immunocytochemistry/ Immunofluorescence: p38 beta/MAPK11 Antibody [NBP2-98810]

Immunocytochemistry/ Immunofluorescence: p38 beta/MAPK11 Antibody [NBP2-98810]

Immunocytochemistry/Immunofluorescence: p38 beta/MAPK11 Antibody [NBP2-98810] - Staining of MAPK11 in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS,blocked with 10% serum, and incubated with rabbit anti-HUMAN MAPK11 polyclonal antibody (dilution ratio: 1:1000) at 4? overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green).Positive staining was localized to cytoplasm and nucleus.
Immunohistochemistry-Paraffin: p38 beta/MAPK11 Antibody [NBP2-98810]

Immunohistochemistry-Paraffin: p38 beta/MAPK11 Antibody [NBP2-98810]

Immunohistochemistry-Paraffin: p38 beta/MAPK11 Antibody [NBP2-98810] - Immunochemical staining of human p38 beta/MAPK11 in human breast carcinoma with rabbit polyclonal antibody at 1:1000 dilution, formalin-fixed paraffin embedded sections.

Applications for p38 beta/MAPK11 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000

Immunohistochemistry-Paraffin

1:500-1:2000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p38 beta/MAPK11

MAPK11 is encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Long Name

Mitogen-Activated Protein Kinase 11

Alternate Names

MAPK11, MPK11, p38b, p38beta, PRKM11, SAPK2B

Gene Symbol

MAPK11

Additional p38 beta/MAPK11 Products

Product Documents for p38 beta/MAPK11 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p38 beta/MAPK11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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