p38 beta/MAPK11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25035

Novus Biologicals, part of Bio-Techne
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NBP3-25035
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (97%), Rat (97%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all p38 beta/MAPK11 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein p38 beta/MAPK11 using the following amino acid sequence: EDEPEAEPYDESVEAKERTLEEWKELTYQEVL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for p38 beta/MAPK11 Antibody

p38 beta/MAPK11 Antibody Immunocytochemistry/Immunofluorescence: p38 beta/MAPK11 Antibody [NBP3-25035]

Immunocytochemistry/Immunofluorescence: p38 beta/MAPK11 Antibody [NBP3-25035]

Staining of human cell line MCF-7 shows localization to cytosol.

Applications for p38 beta/MAPK11 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 µg/ml
Application Notes
For ICC/IF, we recommend using a combination of PFA and Triton X-100. This will give you the optimal results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p38 beta/MAPK11

MAPK11 is encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

Long Name

Mitogen-Activated Protein Kinase 11

Alternate Names

MAPK11, MPK11, p38b, p38beta, PRKM11, SAPK2B

Gene Symbol

MAPK11

Additional p38 beta/MAPK11 Products

Product Documents for p38 beta/MAPK11 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for p38 beta/MAPK11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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