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p63/TP73L Antibody (CL3748)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05501

Novus Biologicals, part of Bio-Techne
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NBP3-05501-100ul
NBP3-05501-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (99%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL3748

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: CACPGRDRKADEDSIRKQQVSDSTKNGDAFRQNTHGIQMTSIKKRRSPDDELLYLPVRGRETYEMLLKIKESLELMQYLPQHTIETYRQQQQQQHQ

Epitope

MQYLPQHTIETYRQQ

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for p63/TP73L Antibody (CL3748)

Western Blot: p63/TP73L Antibody (CL3748) [NBP3-05501]

Western Blot: p63/TP73L Antibody (CL3748) [NBP3-05501]

Western Blot: p63/TP73L Antibody (CL3748) [NBP3-05501] - Analysis in human cell line RT-4 and human cell line U-251 MG.
Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501] - Staining of human prostate shows nuclear immunoreactivity in basal epithelial cells.
Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501]

Immunohistochemistry-Paraffin: p63/TP73L Antibody (CL3748) [NBP3-05501] - Staining of human cervix shows strong nuclear immunoreactivity in epithelial cells.

Applications for p63/TP73L Antibody (CL3748)

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

1 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: p63/TP73L

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Long Name

Tumor Protein 63

Alternate Names

EEC3, KET, OFC8, p40, p51, p73L, SHFM4, TP63, TP73L

Gene Symbol

TP63

Additional p63/TP73L Products

Product Documents for p63/TP73L Antibody (CL3748)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for p63/TP73L Antibody (CL3748)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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