PACE4/PCSK6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87354

Novus Biologicals, part of Bio-Techne
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NBP1-87354
NBP1-87354-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PACE4/PCSK6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTLSSRGPHTFLRMDPQVKWLQQQEVKRRVKR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PACE4/PCSK6 Antibody

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354] - Staining of human cerebellum shows moderate granular cytoplasmic positivity in purkinje cells.
Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.
PACE4/PCSK6 Antibody

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354] -

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP1-87354] -Staining of human placenta shows moderate cytoplasmic granular positivity in trophoblastic cells.
View 2 more images

Applications for PACE4/PCSK6 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 -1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PACE4/PCSK6

The protein encoded by the PACE4 gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Long Name

Proprotein Convertase Subtilisin/Kexin Type 6

Alternate Names

PACE4, PCSK6, Proprotein Convertase 6, SPC4

Gene Symbol

PCSK6

Additional PACE4/PCSK6 Products

Product Documents for PACE4/PCSK6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PACE4/PCSK6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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