PACE4/PCSK6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14443

Novus Biologicals, part of Bio-Techne
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NBP3-14443
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (93%), Equine (100%), Monkey (100%), Mouse (93%), Primate (100%), Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

1 mg/ml

View all PACE4/PCSK6 Antibodies »

Product Specifications

Immunogen

Synthetic 14 amino acid peptide from Cys-rich motif (CRM) region of human PACE4/PCSK6.

Epitope

Internal

Reactivity Notes

Expected reactivity based on percent sequence identity: Turkey, Chicken (86%)

Specificity

Human PACE4/PCSK6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PACE4/PCSK6 Antibody

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP3-14443]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP3-14443]

Immunohistochemistry-Paraffin: PACE4/PCSK6 Antibody [NBP3-14443] - PACE4/PCSK6 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Applications for PACE4/PCSK6 Antibody

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Immunohistochemistry with formalin-fixed paraffin-embedded tissues requires pretreatment with Proteinase K..

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PACE4/PCSK6

The protein encoded by the PACE4 gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq)

Long Name

Proprotein Convertase Subtilisin/Kexin Type 6

Alternate Names

PACE4, PCSK6, Proprotein Convertase 6, SPC4

Gene Symbol

PCSK6

Additional PACE4/PCSK6 Products

Product Documents for PACE4/PCSK6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PACE4/PCSK6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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