PAK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-60456

Novus Biologicals, part of Bio-Techne
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NB100-60456
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all PAK2 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human p21 (CDKN1A)-activated kinase 2 using the numbering given in entry NP_002568.2 (GeneID 5062).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PAK2 Antibody

Western Blot: PAK2 Antibody [NB100-60456]

Western Blot: PAK2 Antibody [NB100-60456]

Western Blot: PAK2 Antibody [NB100-60456] - Detection of Human and Mouse PAK2 on HeLa whole cell lysate using NB100-60456. PAK2 was also immunoprecipitated by rabbit anti-PAK2 antibodies NB100-60457 and Another PAK2.

Applications for PAK2 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PAK2

PAK2 (p21-activated kinase 2) is part of the family of PAK serine/threonine p21-activating protein kinases involved in cell survival, migration, and invasion. The PAK family of proteins mediates signals from extracellular stimuli to the cytoplasm and nucleus via its association with the small GTP-binding proteins Cdc42 and Rac. PAK2 has been shown to play a specific role in apoptosis and cytoskeletal dynamics. During caspase-mediated apoptosis, PAK2 is cleaved and the C-terminal myristoylated fragment mediates cell death and actin reorganization via the JNK signaling pathway.

Long Name

p21-activated Kinase 2

Alternate Names

gamma-PAK, PAK65, S6/H4 Kinase

Entrez Gene IDs

5062 (Human); 224105 (Mouse)

Gene Symbol

PAK2

UniProt

NP_002568.2 (Human)

Additional PAK2 Products

Product Documents for PAK2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PAK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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