PAK2 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
75 results for "PAK2" in Products
75 results for "PAK2" in Products
PAK2 Products
PAK (p21-activated kinases) are a family of serine/threonine kinases within the STE ser/thr protein kinase superfamily that play roles in various oncogenic signaling pathways. Cytoskeletal remodeling, motility, proliferation, and aberrant response to apoptosis and mitosis signals are among oncogenic cell functions coordinated by PAK family members. Group I (PAK1, PAK2 and PAK3, also called alpha, gamma and beta, respectively) contain auto-inhibitory and SH3 domains, in addition to the p21-binding and kinase domains present in Group II (PAK4, PAK6 and PAK7).
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PAK2 AntibodyBSA Free [NBP1-76720]](https://resources.bio-techne.com/images/products/PAK2-Antibody-Western-Blot-NBP1-76720-img0007.jpg "Western Blot: PAK2 AntibodyBSA Free [NBP1-76720]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PAK2 AntibodyBSA Free [NBP1-76721]](https://resources.bio-techne.com/images/products/PAK2-Antibody-Western-Blot-NBP1-76721-img0006.jpg "Western Blot: PAK2 AntibodyBSA Free [NBP1-76721]")
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #677411 |
| Applications: | WB |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #2Y7I2 |
| Applications: | WB, ICC/IF |
![Western Blot: PAK2 Antibody (2Y7I2) [NBP3-16433]](https://resources.bio-techne.com/images/products/PAK2-Antibody-2Y7I2-Western-Blot-NBP3-16433-img0004.jpg "Western Blot: PAK2 Antibody (2Y7I2) [NBP3-16433]")
Recombinant monoclonal antibody expressed in HEK293F cells
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6D12 |
| Applications: | WB, ELISA, Flow, IP |
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #3B5 |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: PAK2 Antibody (3B5)BSA Free [NBP1-47542]](https://resources.bio-techne.com/images/products/PAK2-Antibody-3B5-Western-Blot-NBP1-47542-img0006.jpg "Western Blot: PAK2 Antibody (3B5)BSA Free [NBP1-47542]")
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1E1 |
| Applications: | WB, ELISA, Func |
![Western Blot: PAK2 Antibody (1E1) [H00005062-M01]](https://resources.bio-techne.com/images/products/PAK2-Antibody-1E1-Western-Blot-H00005062-M01-img0003.jpg "Western Blot: PAK2 Antibody (1E1) [H00005062-M01]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF, KO |
![Western Blot: PAK2 AntibodyAzide and BSA Free [NBP3-03354]](https://resources.bio-techne.com/images/products/PAK2-Antibody-Western-Blot-NBP3-03354-img0001.jpg "Western Blot: PAK2 AntibodyAzide and BSA Free [NBP3-03354]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, IP |
![Western Blot: PAK2 Antibody [NB100-60456]](https://resources.bio-techne.com/images/products/PAK2-Antibody-Western-Blot-NB100-60456-img0002.jpg "Western Blot: PAK2 Antibody [NB100-60456]")
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Applications: | AC |
| Applications: | AC |
Highly potent PAK1 and PAK2 inhibitor
| Chemical Name: | 2-[[[2-[[3-(Ethylsulfonyl)-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-fluoro-4-pyrimidinyl][5-(hydroxymethyl)-2-methylphenyl]amino]methyl]benzonitrile |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Primate |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Potent PAK inhibitor; brain penetrant and orally bioavailable
| Chemical Name: | 6-(2,4-Dichlorophenyl)-8-ethyl-2-[[3-fluoro-4-(1-piperazinyl)phenyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one |
| Purity: | ≥98% (HPLC) |
