Park7/DJ-1 Antibody (S04-6H5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20087

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-20087-100ul
NBP3-20087-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S04-6H5

Concentration

0.3 mg/ml

View all Park7/DJ-1 Antibodies »

Product Summary for Park7/DJ-1 Antibody (S04-6H5)

Immunogen

A synthetic peptide of human Park7/DJ-1 (Uniprot # Q99497)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Park7/DJ-1 Antibody (S04-6H5)

Western Blot: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Western Blot: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Western Blot: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087] - Western blot detection of Park7/DJ-1 in K562, Rat Brain, C6, 3T3, Hela cell lysates using NBP3-20087 (1:1000 diluted). Predicted band size: 20kDa. Observed band size: 22kDa.
Immunocytochemistry/ Immunofluorescence: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Immunocytochemistry/ Immunofluorescence: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Immunocytochemistry/Immunofluorescence: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087] - Immunofluorescence of Park7/DJ-1 (green) in Hela using NBP3-20087 at dilution 1/2, and DAPI (blue)
Immunohistochemistry-Paraffin: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Immunohistochemistry-Paraffin: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087]

Immunohistochemistry-Paraffin: Park7/DJ-1 Antibody (S04-6H5) [NBP3-20087] - Immunohistochemistry of Park7/DJ-1 in paraffin-embedded Human tonsil using NBP3-20087 at dilution 1/100

Applications for Park7/DJ-1 Antibody (S04-6H5)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/20-1/100

Immunohistochemistry

1/50-1/200

Western Blot

1/2000-1/10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Park7/DJ-1

PARK7, also known as DJ-1, is a member of the peptidase C56 protein family. The PARK-7 protein is a positive regulator of androgen receptor-dependent transcription. It has also been reported to be a potential sensor for oxidative stress, a redox-sensitive chaperone, and a key protein for preventing neuronal oxidative stress and cell death.

PARK7 is highly expressed in pancreas, kidney, skeletal muscle, liver, testis and heart, and is detected at slightly lower levels in placenta and brain. The protein is also detected in astrocytes, Sertoli cells, spermatogonia, spermatids and spermatozoa.

Defects in this gene cause the autosomal recessive neurodegenerative disorder early-onset Parkinson's disease 7.

Long Name

Parkinson Disease 7

Alternate Names

DJ-1, DJ1

Gene Symbol

PARK7

Additional Park7/DJ-1 Products

Product Documents for Park7/DJ-1 Antibody (S04-6H5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Park7/DJ-1 Antibody (S04-6H5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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