Parvalbumin alpha Antibody (PVALB/7601) [DyLight 680]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27001FR

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin

Label

DyLight 680 (Excitation = 692 nm, Emission = 712 nm)

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # PVALB/7601

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Parvalbumin alpha Antibodies »

Product Specifications

Immunogen

Recombinant fragment (around aa1-110) of human Parvalbumin alpha protein (exact sequence is proprietary)

Localization

Nucleus, Cell junctions

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Parvalbumin alpha Antibody (PVALB/7601) [DyLight 680]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Parvalbumin alpha

Parvalbumin alpha is a 12 kDa member of the parvalbumin family of Ca2+-binding proteins. In human, it is expressed in intrafusal muscle fibers, plus GABAergic interneurons and cerebellar Purkinje and basket cells. It presumably acts as a Ca2+ buffer that shortens the duration of fiber contraction. Human Parvalbumin is 110 amino acids (aa) in length. It contains two EF-hand domains (aa 39 - 74 and 78 - 110) that bind calcium. There are three potential isoform variants. One shows an alternate start site at Met33, a second shows a six aa substitution for the C-terminal nine amino acids and a third shows a deletion of Gly99 - Val100. Human Parvalbumin alpha is 51% aa identical to human Parvalbumin beta and is 87% plus 92% aa identical to mouse and rat Parvalbumin, respectively.

Alternate Names

PVALB

Gene Symbol

PVALB

Additional Parvalbumin alpha Products

Product Documents for Parvalbumin alpha Antibody (PVALB/7601) [DyLight 680]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Parvalbumin alpha Antibody (PVALB/7601) [DyLight 680]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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