Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, SDS-Page, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI8B5

Concentration

1 mg/ml

View all Patched 2/PTCH2 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 79-392 of human PTCH2 (NP_003729) produced in E.coli.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

130.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Patched 2/PTCH2 Antibody (OTI8B5)

SDS-PAGE: Patched 2/PTCH2 Antibody (OTI8B5) [NBP2-45440]

SDS-PAGE: Patched 2/PTCH2 Antibody (OTI8B5) [NBP2-45440]

SDS-Page: Patched 2/PTCH2 Antibody (OTI8B5) [NBP2-45440] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTCH2.

Applications for Patched 2/PTCH2 Antibody (OTI8B5)

Application
Recommended Usage

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Patched 2/PTCH2

Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.

Alternate Names

ptc2, PTCH2

Gene Symbol

PTCH2

Additional Patched 2/PTCH2 Products

Product Documents for Patched 2/PTCH2 Antibody (OTI8B5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Patched 2/PTCH2 Antibody (OTI8B5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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