Patched 2/PTCH2 Products
Patched 2 (Ptch2) is a 180 - 200 kDa 12 transmembrane member of the Patched family. Human PTCH2 is 1203 amino acids (aa) in length. It has two terminal cytoplasmic domains, one between aa 1 - 57, and a second between aa 1115 - 1203. Together with Smoothened (SMO), Ptch2 forms a membrane complex that serves as a receptor for Sonic Hedgehog (SHH).
Human Ptch2 likely has two isoforms. One shows an eight aa extension of the C-terminus, while a second shows a four aa substitution for the C-terminal 61 amino acids (aa 1143 - 1203). Over the first extracellular loop human Patched 2 shares 95% and 96% aa sequence identity with mouse and canine Patched 2, respectively.
68 results for "Patched 2/PTCH2" in Products
68 results for "Patched 2/PTCH2" in Products
Patched 2/PTCH2 Products
Patched 2 (Ptch2) is a 180 - 200 kDa 12 transmembrane member of the Patched family. Human PTCH2 is 1203 amino acids (aa) in length. It has two terminal cytoplasmic domains, one between aa 1 - 57, and a second between aa 1115 - 1203. Together with Smoothened (SMO), Ptch2 forms a membrane complex that serves as a receptor for Sonic Hedgehog (SHH).
Human Ptch2 likely has two isoforms. One shows an eight aa extension of the C-terminus, while a second shows a four aa substitution for the C-terminal 61 amino acids (aa 1143 - 1203). Over the first extracellular loop human Patched 2 shares 95% and 96% aa sequence identity with mouse and canine Patched 2, respectively.
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
![Western Blot: Patched 2/PTCH2 AntibodyBSA Free [NB200-119]](https://resources.bio-techne.com/images/products/Patched-2-Antibody-Western-Blot-NB200-119-img0002.jpg "Western Blot: Patched 2/PTCH2 AntibodyBSA Free [NB200-119]")
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, WB, PAGE |
![SDS-PAGE: Patched 2/PTCH2 Antibody (OTI8B5) [NBP2-45440]](https://resources.bio-techne.com/images/products/Patched-2-PTCH2-Antibody-OTI8B5-SDS-Page-NBP2-45440-img0003.jpg "SDS-PAGE: Patched 2/PTCH2 Antibody (OTI8B5) [NBP2-45440]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: Patched 2/PTCH2 Antibody [NBP1-59457]](https://resources.bio-techne.com/images/products/Patched-2-Antibody-Western-Blot-NBP1-59457-img0002.jpg "Western Blot: Patched 2/PTCH2 Antibody [NBP1-59457]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, CyTOF-ready, ICFlow |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #403438 |
| Applications: | WB, IHC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #865619 |
| Applications: | IHC |
Hedgehog (Hh) pathway antagonist, inhibits ciliogenesis; also inhibits dynein
| Alternate Names: | HPI-4 |
| Chemical Name: | 2,4-Dichloro-α-(3,4-4-oxo-2(1H)-quinazolinylidene)-β-oxobenzenepropanenitrile |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #OTI8B5 |
| Applications: | IHC, PAGE |