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PCNA Antibody (PCNA/8633R) [HRP]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24133H

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-24133H

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

HRP

Antibody Source

Recombinant Monoclonal Rabbit IgG Kappa Clone # PCNA/8633R

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for PCNA Antibody (PCNA/8633R) [HRP]

Immunogen

Recombinant full-length human PCNA protein

Localization

Nucleus. Cytoplasm.

Marker

G1- & S-phase Marker

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG Kappa

Applications for PCNA Antibody (PCNA/8633R) [HRP]

Application
Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PCNA

Proliferating Cell Nuclear Antigen (PCNA) is a DNA polymerase that is essential for DNA replication, excision and mismatch repair pathways. PCNA is a "DNA clamp" which binds to the CDK inhibitor p21, the structure-specific endonucleases Fen1 and XPG, and DNA cytosine 5-methyltransferase (MCMT). PCNA is a potentially useful marker of cells with proliferative potential and for identifying the proliferation status of tumor tissue (i.e. relevant to prognosis). PCNA antibodies are also useful tools for DNA repair and cancer research.

Long Name

Proliferating Cell Nuclear Antigen

Alternate Names

Cyclin, DNA polymerase delta auxiliary protein, MGC8367, proliferating cell nuclear antigen

Gene Symbol

PCNA

Additional PCNA Products

Product Documents for PCNA Antibody (PCNA/8633R) [HRP]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PCNA Antibody (PCNA/8633R) [HRP]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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