PDGFR alpha Antibody (BLR128H)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14711

Recombinant Monoclonal
Novus Biologicals, part of Bio-Techne
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NBP3-14711
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit Clone # BLR128H

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PDGF R alpha Antibodies »

Product Specifications

Immunogen

residues 24-525 (ECD)

Clonality

Monoclonal

Host

Rabbit

Scientific Data Images for PDGFR alpha Antibody (BLR128H)

Immunoprecipitation: PDGFR alpha Antibody (BLR128H) [NBP3-14711]

Immunoprecipitation: PDGFR alpha Antibody (BLR128H) [NBP3-14711]

Immunoprecipitation: PDGFR alpha Antibody [NBP3-14711] - Samples: Whole cell lysate (1 mg forIP; 5% of IP loaded) from NCI-H1703 cells prepared usingNETN lysis buffer. Antibodies: Rabbit anti-PDGFR alpharecombinant monoclonal antibody used for IP at 20 ul/mg lysate. PDGFR alpha was alsoimmunoprecipitated by rabbit anti-PDGFR alpha antibody. For blotting immunoprecipitated PDGFRalpha, was used at 1:1000. Chemiluminescencewith an exposure time of 75 seconds.

Applications for PDGFR alpha Antibody (BLR128H)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

>95%

Formulation

Borate Buffered Saline (BBS) pH 8.2 with , BSA Free

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: PDGF R alpha

Platelet-derived growth factor receptors exhibit tyrosine-protein kinase activity and have been implicated in the control of cell proliferation, survival and migration. PDGF receptors, PDGFR-alpha and PDGFR-beta, have 5 extracellular immunoglobulin-like domains and an intracellular tyrosine kinase domain. Upon binding a PDGF, the receptors form homo-and heterodimers. Dimerization of the receptors results in phosphorylation in the complex. More than 10 different SH2-domain-containing molecules have been shown to bind to different autophosphorylation sites in the PDGF-alpha and beta receptors. PDGF alpha receptors are expressed in oligodendrocyte progenitor cells and PDGF beta receptors are expressed on neurons.

Long Name

Platelet-derived Growth Factor Receptor alpha

Alternate Names

CD140a, PDGFR alpha, PDGFRA

Gene Symbol

PDGFRA

Additional PDGF R alpha Products

Product Documents for PDGFR alpha Antibody (BLR128H)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PDGFR alpha Antibody (BLR128H)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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