PEA-15 Antibody (4D2) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-05544B

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NBP3-05544

Alexa Fluor 350

NBP3-05544AF350

Alexa Fluor 405

NBP3-05544AF405

Alexa Fluor 488

NBP3-05544AF488

Alexa Fluor 532

NBP3-05544AF532

Alexa Fluor 594

NBP3-05544AF594

Alexa Fluor 647

NBP3-05544AF647

Alexa Fluor 700

NBP3-05544AF700

Alexa Fluor 750

NBP3-05544AF750

Allophycocyanin

NBP3-05544APC

CoraFluor 1

NBP3-05544CL1

DyLight 350

NBP3-05544UV

DyLight 405

NBP3-05544V

DyLight 488

NBP3-05544G

DyLight 550

NBP3-05544R

DyLight 594

NBP3-05544DL594

DyLight 650

NBP3-05544C

DyLight 680

NBP3-05544FR

DyLight 755

NBP3-05544IR

FITC

NBP3-05544F

HRP

NBP3-05544H

Janelia Fluor 525

NBP3-05544JF525

Janelia Fluor 549

NBP3-05544JF549

Janelia Fluor 646

NBP3-05544JF646

Janelia Fluor 669

NBP3-05544JF669

mFluor Violet 450 SE

NBP3-05544MFV450

mFluor Violet 500 SE

NBP3-05544MFV500

mFluor Violet 610 SE

NBP3-05544MFV610

PE

NBP3-05544PE

PerCP

NBP3-05544PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat, Bovine

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Biotin

Antibody Source

Monoclonal Mouse IgG₁ Clone # 4D2

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PEA-15 Antibodies »

Product Specifications

Immunogen

Full length human PEA-15 as expressed in and purified from E. coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG₁

Applications for PEA-15 Antibody (4D2) [Biotin]

Application

Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PEA-15

PEA-15 (phosphoprotein enriched in astrocytes) exists in an non-phosphorylated form (N), and two phosphorylated forms, Pa and Pb. PEA-15 is an endogenous substrate for PKC, which mediates the transition from Pa to Pb. The level of PEA-15 phosphorylation changes upon depolymerization or stabilization of tubulins, indicating that PEA-15 co-localizes with microtubules. The first 80 amino acids of PEA-15 correspond to the death effector domain (DED), which is a domain found in proteins that regulate apoptotic signaling pathways. The DED domain is necessary for PEA-15 to block Ras suppression. Although PEA-15 is predominantly expressed in the central nervous system, low levels of PEA-15 are expressed in liver and kidney, and higher levels in muscle. PEA-15 is also referred to as PED, phosphoprotein enriched in diabetes, for its elevated expression in type 2 diabetic patients.

Long Name

Phosphoprotein Enriched in Astrocytes 15

Alternate Names

HMAT1, HUMMAT1H, MAT1H, PEA15, PED

Gene Symbol

PEA15

Additional PEA-15 Products

Product Documents for PEA-15 Antibody (4D2) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PEA-15 Antibody (4D2) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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