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Pentraxin 3/TSG-14 Antibody (2B10)

Novus Biologicals, part of Bio-Techne | Catalog # H00005806-M02

Novus Biologicals, part of Bio-Techne
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H00005806-M02

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2B10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

PTX3 (NP_002843, 282 a.a. ~ 380 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. SLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYV

Localization

Secreted

Specificity

PTX3 - pentraxin-related gene, rapidly induced by IL-1 beta

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Pentraxin 3/TSG-14 Antibody (2B10)

Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - PTX3 monoclonal antibody (M02), clone 2B10. Analysis of PTX3 expression in U-2 OS.
Immunocytochemistry/ Immunofluorescence: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Immunocytochemistry/ Immunofluorescence: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Immunocytochemistry/Immunofluorescence: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - Analysis of monoclonal antibody to PTX3 on HeLa cell. Antibody concentration 10 ug/ml.
Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02]

Western Blot: Pentraxin 3/TSG-14 Antibody (2B10) [H00005806-M02] - Western Blot analysis of PTX3 expression in PC-12 ( Cat # L012V1 ).

Applications for Pentraxin 3/TSG-14 Antibody (2B10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IF and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Pentraxin 3/TSG-14

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins (C-reactive protein and serum amyloid P component) and containing a unique N-terminal domain. The protein is a soluble pattern recognition receptor and represents a nonredundant component of the humoral innate immunity against selected pathogens. PTX3 is rapidly produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It interacts with several ligands, including growth factors, extracellular matrix components and selected pathogens. PTX3 has been implicated in vascular damage, angiogenesis, atherosclerosis, and restenosis.

Long Name

Tumor Necrosis Factor Stimulated Gene 14

Alternate Names

PTX3, TSG-14, TSG14

Entrez Gene IDs

5806 (Human)

Gene Symbol

PTX3

OMIM

602492 (Human)

UniProt

Additional Pentraxin 3/TSG-14 Products

Product Documents for Pentraxin 3/TSG-14 Antibody (2B10)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Pentraxin 3/TSG-14 Antibody (2B10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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