PHKG2 Antibody (2B8)

Novus Biologicals, part of Bio-Techne | Catalog # H00005261-M05

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Lambda Clone # 2B8

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PHKG2 Antibodies »

Product Specifications

Immunogen

PHKG2 (AAH02541.1, 1 a.a. ~ 406 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MTLDVGPEDELPDWAAAKEFYQKYDPKDVIGRGVSSVVRRCVHRATGHEFAVKIMEVTAERLSPEQLEEVREATRRETHILRQVAGHPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDETHPGYGKEVDLWACGVILFTLLAGSPPFWHRRQILMLRMIMEGQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQHPFFERCEGSQPWNLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNCAFRLYGHWVKKGEQQNRAALFQHRPPGPFPIMGPEEEGDSAAITEDEAVLVLG

Specificity

PHKG2 (2B8)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Lambda

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for PHKG2 Antibody (2B8)

Western Blot: PHKG2 Antibody (2B8) [H00005261-M05]

Western Blot: PHKG2 Antibody (2B8) [H00005261-M05]

Western Blot: PHKG2 Antibody (2B8) [H00005261-M05] - Analysis of PHKG2 expression in transfected 293T cell line by PHKG2 monoclonal antibody (M05), clone 2B8. Lane 1: PHKG2 transfected lysate (Predicted MW: 46.4 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: PHKG2 Antibody (2B8) [H00005261-M05]

Immunocytochemistry/ Immunofluorescence: PHKG2 Antibody (2B8) [H00005261-M05]

Immunocytochemistry/Immunofluorescence: PHKG2 Antibody (2B8) [H00005261-M05] - Analysis of monoclonal antibody to PHKG2 on HeLa cell. Antibody concentration 10 ug/ml
Sandwich ELISA: PHKG2 Antibody (2B8) [H00005261-M05] - Detection limit for recombinant GST tagged PHKG2 is approximately 10ng/ml as a capture antibody.

Applications for PHKG2 Antibody (2B8)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PHKG2

PHKG2, also known as Phosphorylase b kinase gamma catalytic chain, liver/testis isoform, has 2 isoforms, a 406 amino acid long isoform that is 46 kDa and a short 374 amino acid isoform that is 43 kDa, as catalytic subunit of the phosphorylase b kinase (PHK) mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase and may regulate glycogeneolysis in the testis and phosphorylates PYGM in vitro. Studies on this protein have shown a relationship with the following diseases and disorders: glycogen storage disease, cirrhosis due to liver, phosphorylase kinase deficiency, hepatitis, metabolic disorders, hypotonia malaria, and alcoholism. This protein has interactions with PHKG1, UBE3A, PHKA2, PHKB, and PYGL in PKA signaling, cAMP Pathway, activation of cAMP-dependent PKA, alpha-adrenergic signaling, metabolism of carbohydrates, glycogen breakdown (glycogenolysis), glucose metabolism, calcium signaling pathway and insulin signaling pathway.

Alternate Names

EC 2.7.11, EC 2.7.11.19, GSD9C, PHK-gamma-T, phosphorylase b kinase gamma catalytic chain, testis/liver isoform, Phosphorylase kinase subunit gamma-2, phosphorylase kinase, gamma 2 (testis), Phosphorylase kinase, gamma 2 (testis/liver), PSK-C3

Entrez Gene IDs

5261 (Human)

Gene Symbol

PHKG2

OMIM

172471 (Human)

UniProt

AAH02541 (Human)

Additional PHKG2 Products

Product Documents for PHKG2 Antibody (2B8)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PHKG2 Antibody (2B8)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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