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PHOX2B Antibody (SR1589)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21890

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21890-100ul
NBP3-21890-50ul

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1589

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for PHOX2B Antibody (SR1589)

Immunogen

A synthesized peptide derived from human PHOX2B (Uniprot #: Q99453)

Specificity

Detects endogenous levels of total PHOX2B

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PHOX2B Antibody (SR1589)

Western Blot: PHOX2B Antibody (SR1589) [NBP3-21890] -

Western Blot: PHOX2B Antibody (SR1589) [NBP3-21890] - Western blot analysis using NBP3-21890 in Neuro-2a cell lysate.

Applications for PHOX2B Antibody (SR1589)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:100-1:500

Immunohistochemistry-Paraffin

1:100-1:500

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PHOX2B

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. (provided by RefSeq)

Long Name

Paired-like Homeobox 2b

Alternate Names

NBPhox, PMX2B

Gene Symbol

PHOX2B

Additional PHOX2B Products

Product Documents for PHOX2B Antibody (SR1589)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PHOX2B Antibody (SR1589)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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