PI 3-Kinase p110 gamma Antibody (OTI2B1)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46411

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2A Clone # OTI2B1

Concentration

1 mg/ml

View all PI 3-Kinase p110 gamma Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human PIK3CG(NP_002640) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2A

Theoretical MW

126.3 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PI 3-Kinase p110 gamma Antibody (OTI2B1)

Western Blot: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Western Blot: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Western Blot: PI 3-Kinase p110 gamma Antibody (2B1) [NBP2-46411] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PI 3-Kinase p110.
Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (2B1) [NBP2-46411] - Analysis of Human breast tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (OTI2B1) [NBP2-46411]

Immunohistochemistry: PI 3-Kinase p110 gamma Antibody (2B1) [NBP2-46411] - Analysis of Human pancreas tissue. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min)
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Applications for PI 3-Kinase p110 gamma Antibody (OTI2B1)

Application
Recommended Usage

Immunohistochemistry

1:150

Western Blot

1:1000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PI 3-Kinase p110 gamma

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Long Name

Protein Tyrosine Phosphatase 1G

Alternate Names

p120-PI3K, PI 3Kinase p110 gamma, PI3CG, PI3K-gamma, PIK3CG

Gene Symbol

PIK3CG

Additional PI 3-Kinase p110 gamma Products

Product Documents for PI 3-Kinase p110 gamma Antibody (OTI2B1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PI 3-Kinase p110 gamma Antibody (OTI2B1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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