PI 3-Kinase p85 beta Antibody (PIK3R2/1293) [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-14139B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Unconjugated

NBP3-13736

Alexa Fluor 350

NBP3-14139AF350

Alexa Fluor 405

NBP3-14139AF405

Alexa Fluor 488

NBP3-14139AF488

Alexa Fluor 532

NBP3-14139AF532

Alexa Fluor 594

NBP3-14139AF594

Alexa Fluor 647

NBP3-14139AF647

Alexa Fluor 700

NBP3-14139AF700

Alexa Fluor 750

NBP3-14139AF750

Allophycocyanin

NBP3-14139APC

CoraFluor 1

NBP3-14139CL1

DyLight 350

NBP3-14139UV

DyLight 405

NBP3-14139V

DyLight 488

NBP3-14139G

DyLight 550

NBP3-14139R

DyLight 594

NBP3-14139DL594

DyLight 650

NBP3-14139C

DyLight 680

NBP3-14139FR

DyLight 755

NBP3-14139IR

FITC

NBP3-14139F

HRP

NBP3-14139H

Janelia Fluor 525

NBP3-14139JF525

Janelia Fluor 549

NBP3-14139JF549

Janelia Fluor 646

NBP3-14139JF646

Janelia Fluor 669

NBP3-14139JF669

PE

NBP3-14139PE

PerCP

NBP3-14139PCP

Forumulation

Catalog #

Azide and BSA Free

NBP3-14139

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry-Paraffin, Protein Array

Label

Biotin

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # PIK3R2/1293

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PI 3-Kinase p85 beta Antibodies »

Product Specifications

Immunogen

Recombinant fragment of human PI 3-Kinase p85 beta protein (around aa 520-720) (exact sequence is proprietary) (Uniprot: O00459)

Reactivity Notes

0

Localization

Cytoplasm,golgi apparatus, Nucleus

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for PI 3-Kinase p85 beta Antibody (PIK3R2/1293) [Biotin]

Application

Recommended Usage

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PI 3-Kinase p85 beta

The enzyme phosphatidylinositol 3 kinase (PI3 kinase) is a lipid kinase that generates phosphatidylinositol 3, 4, 5-triphosphate in response to receptor activation in many signal transduction pathways. Class IA PI3Ks exist as a heterodimer of a catalytic 110 kDa (p110) and a regulatory p85 subunit (e.g. p85 beta). p85 beta is an adaptor molecule that regulates the activity of the catalytic p110 subunit by binding to phosphorylated receptor tyrosine kinases (RTKs) through its SH2 domain and mediating the interaction between p110 and the plasma membrane. p85 beta is necessary for insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.

Long Name

Phosphatidylinositol-3-kinase 85 kDa Regulatory Subunit beta

Alternate Names

p85-beta, PI 3Kinase p85 beta, PIK3R2

Gene Symbol

PIK3R2

Additional PI 3-Kinase p85 beta Products

Product Documents for PI 3-Kinase p85 beta Antibody (PIK3R2/1293) [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PI 3-Kinase p85 beta Antibody (PIK3R2/1293) [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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