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PIK3CA Antibody (CL8347)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-88915

Novus Biologicals, part of Bio-Techne
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NBP2-88915

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CL8347

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for PIK3CA Antibody (CL8347)

Immunogen

This antibody was developed against a synthetic peptide corresponding to amino acids: SYSHAGLSNRLARDNELRENDKEQ

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PIK3CA Antibody (CL8347)

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915] - Staining of human stomach cancer shows moderate cytoplasmic positivity in tumor cells.
Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915] - Staining of human endometrium shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915]

Immunohistochemistry-Paraffin: PIK3CA Antibody (CL8347) [NBP2-88915] - Staining of human placenta shows moderate cytoplasmic positivity in trophoblastic cells.

Applications for PIK3CA Antibody (CL8347)

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, pH 7.2, containing 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PIK3CA

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found;

Long Name

PI3-Kinase P110 Subunit Alpha

Alternate Names

CLAPO, CLOVE, CWS5, MCMTC, P110alpha, PI3Kalpha

Gene Symbol

PIK3CA

Additional PIK3CA Products

Product Documents for PIK3CA Antibody (CL8347)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PIK3CA Antibody (CL8347)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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