PINCH1/LIMS1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-46851

Novus Biologicals, part of Bio-Techne
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NBP2-46851
NBP2-46851-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PINCH1 Antibodies »

Product Summary for PINCH1/LIMS1 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MAFSGRARPCIIPENEEIPRAALNTVHEANGTEDERAVSKLQRRHSDVKVY

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (84%), Rat (80%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PINCH1/LIMS1 Antibody

Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-46851]

Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-46851]

Immunohistochemistry-Paraffin: PINCH1/LIMS1 Antibody [NBP2-46851] - Staining of human adrenal gland shows cytoplasmic positivity in glandular cells.

Applications for PINCH1/LIMS1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PINCH1

The protein encoded by the LIMS1 gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. (provided by RefSeq)

Long Name

Particularly Interesting New Cys-His Protein 1

Alternate Names

LIMS1

Gene Symbol

LIMS1

UniProt

B4DPH6 (Human)

Additional PINCH1 Products

Product Documents for PINCH1/LIMS1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PINCH1/LIMS1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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