PITPNB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86864

Novus Biologicals, part of Bio-Techne
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NBP1-86864
NBP1-86864-25ul
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PITPNB Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: CSVQEYQVGQLYSVAEASKNETGGGEGIEVLKNEPYEKDGEKGQYTHKIYHLKSKVPAFVRMIAPEGSLVFHEKAWNAYPYCRTIVTNEYMKDDFFIKIETWHKPDLGTLENVHGLDPNT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PITPNB Antibody

Western Blot: PITPNB Antibody [NBP1-86864]

Western Blot: PITPNB Antibody [NBP1-86864]

Western Blot: PITPNB Antibody [NBP1-86864] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunocytochemistry/ Immunofluorescence: PITPNB Antibody [NBP1-86864]

Immunocytochemistry/ Immunofluorescence: PITPNB Antibody [NBP1-86864]

Immunocytochemistry/Immunofluorescence: PITPNB Antibody [NBP1-86864] - Staining of human cell line U-2 OS shows localization to cytosol & vesicles.
Immunohistochemistry-Paraffin: PITPNB Antibody [NBP1-86864]

Immunohistochemistry-Paraffin: PITPNB Antibody [NBP1-86864]

Immunohistochemistry-Paraffin: PITPNB Antibody [NBP1-86864] - Staining of human urinary bladder shows strong cytoplasmic and membranous positivity in urothelial cells.
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Applications for PITPNB Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PITPNB

PITPNB, also known as Phosphatidylinositol Transfer Protein Beta, has two isoforms that are each approximately 32 kDa with 271 and 272 amino acids, respectively. PITPNB is localized to the cytoplasm and expressed in a variety of tissues, including the brain. PITPNB is responsible for catalyzing the transfer of phosphatidylcholine and phosphatidylinositol between membranes. Pathways in which PITPNB plays a role include phospholipid metabolism and PI/PC transport between the ER and Golgi membranes. Current research on PITPNB is being conducted in relation to obesity, and PITPNB has been shown to interact with Von Hippel Lindau, Ubiquitin C, Lamin A and LMO4.

Alternate Names

phosphatidylinositol transfer protein beta isoform, phosphatidylinositol transfer protein, beta, phosphotidylinositol transfer protein, beta, PI-TP-beta, PtdIns transfer protein beta, PtdInsTP, PtdInsTP beta, VIB1B

Gene Symbol

PITPNB

Additional PITPNB Products

Product Documents for PITPNB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PITPNB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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