PKC eta Antibody (SR1663)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21825

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21825-100ul
NBP3-21825-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1663

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PKC eta Antibodies »

Product Summary for PKC eta Antibody (SR1663)

Immunogen

A synthesized peptide derived from human PKC eta (Uniprot #: P24723)

Specificity

Detects endogenous levels of total PKC eta

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PKC eta Antibody (SR1663)

Western Blot: PKC eta Antibody (SR1663) [NBP3-21825] -

Western Blot: PKC eta Antibody (SR1663) [NBP3-21825] - Western blot analysis using NBP3-21825 in MCF7 cell lysate.

Applications for PKC eta Antibody (SR1663)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PKC eta

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Long Name

Protein kinase C eta type

Alternate Names

EC 2.7.11.13, nPKC-eta, PKC-L, PKCL, PRKCH

Gene Symbol

PRKCH

Additional PKC eta Products

Product Documents for PKC eta Antibody (SR1663)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PKC eta Antibody (SR1663)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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