Placental Lactogen/CSH1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59302

Novus Biologicals, part of Bio-Techne
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NBP1-59302
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all Placental Lactogen/CSH1 Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to CSH1 (chorionic somatomammotropin hormone 1 (placental lactogen)) The peptide sequence was selected from the middle region of CSH1. Peptide sequence SMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for Placental Lactogen/CSH1 Antibody

Western Blot: Placental Lactogen/CSH1 Antibody [NBP1-59302]

Western Blot: Placental Lactogen/CSH1 Antibody [NBP1-59302]

Western Blot: Placental Lactogen/CSH1 Antibody [NBP1-59302] - Antibody Titration: 1.25ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta
Immunohistochemistry-Paraffin: Placental Lactogen/CSH1 Antibody [NBP1-59302]

Immunohistochemistry-Paraffin: Placental Lactogen/CSH1 Antibody [NBP1-59302]

Immunohistochemistry-Paraffin: Placental Lactogen/CSH1 Antibody [NBP1-59302] - Human Stomach Tissue, Epithelial cells of funic gland (Indicated with Arrows) 4-8ug/ml.

Applications for Placental Lactogen/CSH1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Placental Lactogen/CSH1

CSH1 is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

Alternate Names

Choriomammotropin, CSH1, CSMT, Lactogen, PL

Gene Symbol

CSH1

UniProt

P01243 (Human)

Additional Placental Lactogen/CSH1 Products

Product Documents for Placental Lactogen/CSH1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Placental Lactogen/CSH1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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