Plexin A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82544

Novus Biologicals, part of Bio-Techne
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NBP1-82544
NBP1-82544-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (94%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Plexin A1 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDFNQPLGGTVTIEGTPLFVDKDDGLTAVAAYDYRGRTVVFAGTRSGRIRKILVDLSNPGGRPALAYESVVAQEGSPILRDLVLSPNHQYLYAMTEKQVT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Plexin A1 Antibody

Immunocytochemistry/ Immunofluorescence: Plexin A1 Antibody [NBP1-82544]

Immunocytochemistry/ Immunofluorescence: Plexin A1 Antibody [NBP1-82544]

Immunocytochemistry/Immunofluorescence: Plexin A1 Antibody [NBP1-82544] - Immunofluorescent staining of human cell line U-2 OS shows localization to nucleus & cytosol.
Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544]

Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544]

Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544] - Staining of human skeletal muscle shows no positivity in myocytes.
Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544]

Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544]

Immunohistochemistry-Paraffin: Plexin A1 Antibody [NBP1-82544] - Staining of human lung shows strong cytoplasmic postivity in macrophages.
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Applications for Plexin A1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval method is recommended. ICC/IF Fixation Permeabilization, Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Plexin A1

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm

Alternate Names

NOVP, PLXN1, PLXNA1

Gene Symbol

PLXNA1

Additional Plexin A1 Products

Product Documents for Plexin A1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Plexin A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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