PMP70 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-20871

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-20871
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Rat

Cited:

Rat

Predicted:

Mouse (100%). Backed by our 100% Guarantee.

Applications

Validated:

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PMP70 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-PDGREDQKRKGISD corresponding to internal region according to NP_002849.1.

Epitope

C terminus

Reactivity Notes

Rat reactivity reported in scientific literature (PMID: 21248309).

Specificity

This antibody is expected to recognize one isoform (NP_002849.1) only.

Marker

Proxisomal Membrane Marker

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PMP70 Antibody

Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-20871]

Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-20871]

Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-20871] - Staining of Human Testis with antibody at 3.8 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Flow Cytometry: PMP70 Antibody [NBP1-20871]

Flow Cytometry: PMP70 Antibody [NBP1-20871]

Flow Cytometry: PMP70 Antibody [NBP1-20871] - Flow cytometric analysis of paraformaldehyde fixed A431 cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

Applications for PMP70 Antibody

Application
Recommended Usage

Flow Cytometry

10 ug/mL

Immunohistochemistry

2.5 - 3.8 ug/mL

Immunohistochemistry-Paraffin

2.5 - 3.8 ug/mL

Peptide ELISA

Detection limit 1:16000
Application Notes
IHC-P: Human testis shows vesicular staining in Sertoli cells.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PMP70

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Alternate Names

70 kDa peroxisomal membrane protein, ABC43, ATP-binding cassette, sub-family D (ALD), member 3, peroxisomal membrane protein 1 (70kD, Zellweger syndrome), Peroxisomal membrane protein-1 (70kD), PMP70ATP-binding cassette sub-family D member 3, PXMP1dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)), ZWS2

Entrez Gene IDs

5825 (Human); 19299 (Mouse); 25270 (Rat)

Gene Symbol

ABCD3

UniProt

NP_002849.1 (Human)

Additional PMP70 Products

Product Documents for PMP70 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PMP70 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.