Podocin/NPHS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00007827-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Podocin/NPHS2 Antibodies »

Product Specifications

Immunogen

NPHS2 (AAH29141.1, 1 a.a. - 315 a.a.) full-length human protein. MERRARSSSRESRGRGGRTPHKENKRAKAERSGGGRGRQEAGPEPSGSGRAGTPGEPRAPAATVVDVDEVRGSGEEGTEVVALLESERPEEGTKSSGLGACEWLLVLISLLFIIMTFPFSIWFCVKVVQEYERVIIFRLGHLLPGRAKGPGLFFFLPCLDTYHKVDLRLQTLEIPFHEVALDSVTCIWGIKVERIEIKDVRLPAGLQHSLAVEAEAQRQAKVRMIAAEAEKAASESLRMAAEILSGTPAAVQLRYLHTLQSLSTEKPSTVVLPLPFDLLNCLSSPSNRTQGSLPFPSPSKPVEPLNPKKKDSPML

Specificity

NPHS2,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for Podocin/NPHS2 Antibody

Western Blot: Podocin/NPHS2 Antibody [H00007827-D01P]

Western Blot: Podocin/NPHS2 Antibody [H00007827-D01P]

Western Blot: NPHS2 Antibody [H00007827-D01P] - Analysis of NPHS2 expression in mouse kidney.
Western Blot: Podocin/NPHS2 Antibody [H00007827-D01P]

Western Blot: Podocin/NPHS2 Antibody [H00007827-D01P]

Western Blot: NPHS2 Antibody [H00007827-D01P] - Analysis of NPHS2 expression in transfected 293T cell line by NPHS2 polyclonal antibody.Lane 1: NPHS2 transfected lysate(34.40 KDa).Lane 2: Non-transfected lysate.

Applications for Podocin/NPHS2 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for ELISA and WB.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Podocin/NPHS2

This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

Alternate Names

Nephrosis 2, NPHS2, PDCN, SRN1

Entrez Gene IDs

7827 (Human)

Gene Symbol

NPHS2

UniProt

AAH29141.1 (Human)

Additional Podocin/NPHS2 Products

Product Documents for Podocin/NPHS2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Podocin/NPHS2 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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