Podoplanin Antibody (066)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-89552

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 066

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Podoplanin Antibodies »

Product Summary for Podoplanin Antibody (066)

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Podoplanin (Accession#: NP_034459.2; Met1-Lys133).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Podoplanin Antibody (066)

Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552]

Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552]

Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552] - Staining of mouse PDPN in mouse brain with rabbit monoclonal antibody (1:500).
Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552]

Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552]

Immunohistochemistry-Paraffin: Podoplanin Antibody (066) [NBP2-89552] - Staining of mouse PDPN in mouse kidney with rabbit monoclonal antibody (1:500).

Applications for Podoplanin Antibody (066)

Application
Recommended Usage

Immunohistochemistry

1:250-1:1000

Immunohistochemistry-Paraffin

1:250-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Podoplanin

Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.

Long Name

Lung Type-I Cell Membrane-associated Glycoprotein, Isoform A

Alternate Names

Aggrus, Gp38, PDPN, RANDAM-2, T1A-2

Gene Symbol

PDPN

Additional Podoplanin Products

Product Documents for Podoplanin Antibody (066)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Podoplanin Antibody (066)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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