Podoplanin is a well-recognized lymphatic endothelium marker, which can be used to reliably distinguish lymphatic vessels from blood vessels. Podoplanin is a 38 kDa membrane mucoprotein that was originally detected on the surface of rat glomerular epithelial cells (podocytes) and was found to be linked to flattening of foot processes that occurs in glomerular diseases. Podoplanin shows features of a membrane mucoprotein with several conserved O-glycosylation sites. Currently, it is of unknown biological function. Because heavily O-glycosylated mucoproteins were identified recently as counterreceptors for selectins that mediate adhesion of inflammatory cells, it is possible that podoplanin plays a similar role in lymphatic endothelia.

Long Name

Lung Type-I Cell Membrane-associated Glycoprotein, Isoform A

Alternate Names

Aggrus, Gp38, PDPN, RANDAM-2, T1A-2

Gene Symbol

PDPN

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Product Documents for Podoplanin Antibody (rPDPN/6994) [Janelia Fluor® 646]

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COA

SDS

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Product Specific Notices for Podoplanin Antibody (rPDPN/6994) [Janelia Fluor® 646]

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Podoplanin Antibody (rPDPN/6994) [Janelia Fluor® 646]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-20917JF646

Key Product Details

Species Reactivity

Applications

Label

Antibody Source

Concentration

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Product Specifications

Immunogen

Localization

Clonality

Host

Isotype

Applications for Podoplanin Antibody (rPDPN/6994) [Janelia Fluor® 646]

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Podoplanin