Polycystin-1/PKD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52552

Novus Biologicals, part of Bio-Techne
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NBP1-52552
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (100%). Backed by our 100% Guarantee.

Applications

Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Peptide ELISA

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Polycystin-1/PKD1 Antibodies »

Product Specifications

Immunogen

Synthetic peptide C-RTPLRAKNKVHP from the C-terminus of human Polycystin-1/PKD1 (NP_001009944.1; NP_000287.2).

Epitope

C-RTPLRAKNKVHP from the C-Terminus

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (83%), Feline (83%), Canine (83%), Equine (83%).

Specificity

Human PKD1. This antibody is expected to recognize both reported isoforms (NP_001009944.1 and NP_000287.2).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Polycystin-1/PKD1 Antibody

Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552]

Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552]

Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552] - Analysis of anti-PKD1 antibody with human kidney at concentration 3.75 ug/ml.
Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552]

Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552]

Immunohistochemistry-Paraffin: Polycystin-1/PKD1 Antibody [NBP1-52552] - Analysis of anti-PKD1 antibody with human spleen at concentration 3.75 ug/ml.

Applications for Polycystin-1/PKD1 Antibody

Application
Recommended Usage

Immunohistochemistry-Paraffin

3.75 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS (pH 7.3) and 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Polycystin-1/PKD1

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, episilon , zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and episilon are independent of Ca++. On the other hand, nPKC delta and episilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

Alternate Names

Pc-1, PKD1, Polycystin1, TRPP1

Entrez Gene IDs

5310 (Human)

Gene Symbol

PKD1

UniProt

P98161 (Human)

Additional Polycystin-1/PKD1 Products

Product Documents for Polycystin-1/PKD1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Polycystin-1/PKD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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