Potassium Channel Kv2.2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57427

Novus Biologicals, part of Bio-Techne
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NBP2-57427
NBP2-57427-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Potassium Channel Kv2.2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QHISTILLEETPSQGDRPLLGTEVSAPCQGPSKGLSPRFPKQKLFPFSSRERRSFTEIDTGDDEDFLELP

Reactivity Notes

Rat 81%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Potassium Channel Kv2.2 Antibody

Immunocytochemistry/ Immunofluorescence: Potassium Channel Kv2.2 Antibody [NBP2-57427]

Immunocytochemistry/ Immunofluorescence: Potassium Channel Kv2.2 Antibody [NBP2-57427]

Immunocytochemistry/Immunofluorescence: Potassium Channel Kv2.2 Antibody [NBP2-57427] - Staining of human cell line HaCaT shows localization to nucleoli, plasma membrane & centrosome.

Applications for Potassium Channel Kv2.2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Potassium Channel Kv2.2

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. The delayed rectifier-type (IK)channels (Kv1.5, Kv2.1, and Kv2.2) are expressed on all neuronal somata and proximal dendrites and are also found in a wide variety on non-neuronal cells types including pancreatic islets, alveolar cells and cardiac myocytes (Hwang et al., 1993; Yan et al., 2004; Michaelevski et al., 2003). Kv2.1 and Kv2.2 form distinct populations of K+ channels and these subunits are thought to be primarily responsible for IK in superior cervical ganglion cells (Blaine and Ribera, 1998; Burger and Ribera, 1996).

Alternate Names

KCNB2

Gene Symbol

KCNB2

Additional Potassium Channel Kv2.2 Products

Product Documents for Potassium Channel Kv2.2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Potassium Channel Kv2.2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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