PP1 alpha/PPP1A Antibody (6D1) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51600

Novus Biologicals, part of Bio-Techne
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NBP1-51600
NBP1-51600-0.025ml
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Key Product Details

Species Reactivity

Human, Mouse

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6D1

Format

BSA Free

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all PP1 alpha Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human PP1 alpha/PPP1A expressed in E. Coli.

Reactivity Notes

Human, Mouse.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

38 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PP1 alpha/PPP1A Antibody (6D1) - BSA Free

Western Blot: PP1 alpha/PPP1A Antibody (6D1)BSA Free [NBP1-51600]

Western Blot: PP1 alpha/PPP1A Antibody (6D1)BSA Free [NBP1-51600]

Western Blot: PP1 alpha/PPP1A Antibody (6D1) [NBP1-51600] - WB analysis of PPP1A in human cell lysate. Verified customer review from 1DegreeBio.
Western Blot: PP1 alpha/PPP1A Antibody (6D1)BSA Free [NBP1-51600]

Western Blot: PP1 alpha/PPP1A Antibody (6D1)BSA Free [NBP1-51600]

Western Blot: PP1 alpha/PPP1A Antibody (6D1) [NBP1-51600] - Western blot analysis using PPP1A mouse mAb against Hela (1) and NIH/3T3 (2) cell lysate.

Applications for PP1 alpha/PPP1A Antibody (6D1) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Western Blot

1:500-1:2000

Reviewed Applications

Read 1 review rated 4 using NBP1-51600 in the following applications:

Formulation, Preparation, and Storage

Purification

Unpurified

Formulation

Ascites

Format

BSA Free

Preservative

0.03% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PP1 alpha

Protein phosphatase 1 (PP1) is a major eukaryotic protein serine/threonine phosphatase that regulates an enormous variety of cellular functions through the interaction of its catalytic subunit (PP1c) with over fifty different established or putative regulatory subunits (1). The coordinated and reciprocal action of serine/threonine (Ser/Thr) protein kinases and phosphatases produces transient phosphorylation, a fundamental regulatory mechanism for many biological processes. PP1 is ubiquitously distributed and regulates a broad range of cellular functions, including glycogen metabolism, cell-cycle progression and muscle relaxation. PP1 has evolved effective catalytic machinery but lacks substrate specificity. Substrate specificity is conferred upon PP1 through interactions with a large number of regulatory subunits (2). It has been shown that PP1 determines the efficacy of learning and memory by limiting acquisition and favouring memory decline. When PP1 is genetically inhibited during learning, short intervals between training episodes are sufficient for optimal performance (3).

Long Name

Protein Phosphatase 1 Catalytic Subunit alpha

Alternate Names

PPP1A, PPP1CA

Gene Symbol

PPP1CA

Additional PP1 alpha Products

Product Documents for PP1 alpha/PPP1A Antibody (6D1) - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PP1 alpha/PPP1A Antibody (6D1) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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