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PP14/Glycodelin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-89781

Novus Biologicals, part of Bio-Techne
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NBP1-89781
NBP1-89781-25ul

Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for PP14/Glycodelin Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PP14/Glycodelin Antibody

Western Blot: PP14/Glycodelin Antibody [NBP1-89781]

Western Blot: PP14/Glycodelin Antibody [NBP1-89781]

Western Blot: PP14/Glycodelin Antibody [NBP1-89781] - Analysis in human placenta tissue.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781]

Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781]

Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781] - Staining of human testis shows no positivity in cells in seminiferous ducts as expected.
Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781]

Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781]

Immunohistochemistry-Paraffin: PP14/Glycodelin Antibody [NBP1-89781] - Staining of human endometrium shows high expression.

Applications for PP14/Glycodelin Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PP14/Glycodelin

PAEP (Progesterone-associated endometrial protein, glycodelin, PEG, PP14) is a glycoprotein belonging to lipocalin structural superfamily. It shares a sequence homology to beta-lactoglobulins containing a retinol-binding motif and it is mainly produced by secretory and decidualized endometrium in women and by seminal vesicle epithelium in men (1). PAEP function is not clearly understood. However, glycosylated version of PAEP (GdA) has been associated to contraceptive and immunosuppressive activities during reproduction. PAEP is the main protein produced by secretory endometrium during mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Therefore, PAEP has been linked as an ideal biomarker of endometrial activity and function for in vitro fertilization treated women (2).

Long Name

Placental Protein 14

Alternate Names

Glycodelin, PAEP

Gene Symbol

PAEP

Additional PP14/Glycodelin Products

Product Documents for PP14/Glycodelin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PP14/Glycodelin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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