PPP1R3B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-82243

Novus Biologicals, part of Bio-Techne
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NBP1-82243
NBP1-82243-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP1R3B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DRDTFSFDISLPEKIQSYERMEFAVYYECNGQTYWDSNRGKNYRIIRAELKSTQGMTKPHSGPDLGISFDQFGSPRCSYGLF

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPP1R3B Antibody

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243] - Staining in human liver and lymph node tissues . Corresponding PPP1R3B RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243]

Immunohistochemistry-Paraffin: PPP1R3B Antibody [NBP1-82243] - Staining of human lymph node shows only very weak positivity in lymphoid cells.
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Applications for PPP1R3B Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPP1R3B

PPP1R3B, the protein phosphatase-1 (PP1) catalytic subunit (PPP1CA; MIM 176875) is regulated by targeting subunits, such as PP1R3B. PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e., inactivates) glycogen phosphorylase (see PYGL; MIM 232700) and enhances the rate at which it activates glycogen synthase (see GYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[supplied by OMIM]

Alternate Names

FLJ14005, FLJ34675, GL, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, PPP1R4PP1 subunit R4, protein phosphatase 1 regulatory subunit 3B, Protein phosphatase 1 regulatory subunit 4, Protein phosphatase 1 subunit GL, protein phosphatase 1, regulatory (inhibitor) subunit 3B

Gene Symbol

PPP1R3B

Additional PPP1R3B Products

Product Documents for PPP1R3B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPP1R3B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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