PRAS40 Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41221B

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Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP2-41221AF350

Alexa Fluor 405

NBP2-41221AF405

Alexa Fluor 488

NBP2-41221AF488

Alexa Fluor 532

NBP2-41221AF532

Alexa Fluor 594

NBP2-41221AF594

Alexa Fluor 647

NBP2-41221AF647

Alexa Fluor 700

NBP2-41221AF700

Alexa Fluor 750

NBP2-41221AF750

CoraFluor 1

NBP2-41221CL1

DyLight 350

NBP2-41221UV

DyLight 405

NBP2-41221V

DyLight 488

NBP2-41221G

DyLight 550

NBP2-41221R

DyLight 594

NBP2-41221DL594

DyLight 650

NBP2-41221C

DyLight 680

NBP2-41221FR

DyLight 755

NBP2-41221IR

FITC

NBP2-41221F

HRP

NBP2-41221H

Janelia Fluor 525

NBP2-41221JF525

Janelia Fluor 549

NBP2-41221JF549

Janelia Fluor 646

NBP2-41221JF646

Janelia Fluor 669

NBP2-41221JF669

mFluor Violet 450 SE

NBP2-41221MFV450

mFluor Violet 500 SE

NBP2-41221MFV500

mFluor Violet 610 SE

NBP2-41221MFV610

PerCP

NBP2-41221PCP

Forumulation

Catalog #

BSA Free

NBP2-41221

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Biotin

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PRAS40 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid peptide near the carboxy terminus of human AKT1S1. The immunogen is located within amino acids 190 - 240 of AKT1S1. Amino Acid Squence: RTEARSSDEENGPPSSPDL

Reactivity Notes

0

Specificity

At least three isoforms of AKT1S1 are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for PRAS40 Antibody [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: PRAS40

Proline Rich Akt Substrate (PRAS40) is a 40 kDa substrate of Akt. Akt and PRAS40 can be found in the phosphoinositide 3 kinase (PI3K) pathway, which plays a role in glucose uptake, cell growth, and apoptosis inhibition. PRAS40 is a 14-3-3 binding protein that reacts with insulin, but whose precise function is not yet known. It may bind SH3 and WW domain containing proteins resulting in a change of function. Activated Akt phosphorylates PRAS40 on threonine 246. Mutation of PRAS40 threonine 246 has been shown to be apoptotic.

Long Name

40 kDa Proline-rich Akt1 Substrate

Alternate Names

AKT1S1, Lobe

Gene Symbol

AKT1S1

Additional PRAS40 Products

Product Documents for PRAS40 Antibody [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for PRAS40 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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